LIPIDS AND IMMUNOLOGICAL REACTIONS

Lipids and Immunological Reactions

1. Specific precipitates resulting from the interaction of the homologous capsular polysaccharide and Type I antipneumococcus horse and rabbit sera have been analyzed by gasometric micro methods for total nitrogen, lipid nitrogen, and lipid carbon. 2. Lipid may, under certain conditions, form as much as 51 per cent or as little as 4 per cent by weight of specific precipitates. 3. The total lipi...

Biological and Immunological Reactions in Parasitic Diseases

Processed antigen reacts selectively with lymphocytes bearing .appropriate surface immunoglobulin molecules resulting in the clonal proliferation of these cells, produc­ing circulating immunoglobulin (humoral immunity) or non-circulating immunoglobulins (cellular immunity).  High levels of circulating immunoglobulins (lgM & lgG) occur in protozoa and helminths infections. Reaginic antibodies a...

Lipoids and Immunological Reactions

It has been demonstrated that the removal of lipoids from Type I antipneumococcus horse serum causes a loss of the visible phenomena of type specific agglutination and precipitation, and in the case of rabbit serum a marked reduction in these properties. Initial activity of the type specific antibody can be restored to extracted immune horse serum by the addition of lecithin, and to rabbit seru...

Lipids and Immunological Reactions Iii. Lipid Content of Specific Precipitates from Type I Antipneumococcus Sera

It has been reported (1, 2) that the presence of certain lipids is essential to the in vitro demonstration of type-specific agglutination and precipitation by antipneumococcus sera. I t was suggested that the antibody of antipneumococcus serum might be a phosphatideglobulin complex, the nature of the lipid fraction being dependent upon the species derivation of the antibody. Because of the minu...

Immunological reactions in heart disease.